Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists-Reference-Cited by-同舟云学术

Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists

Published:2018-07-04 Issue:15 Volume:13 Page:1580-1587
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Börgel Frederik¹,Szermerski Marina¹,Schreiber Julian A.¹,Temme Louisa¹,Strutz‐Seebohm Nathalie²,Lehmkuhl Kirstin¹,Schepmann Dirk¹³,Ametamey Simon M.⁴,Seebohm Guiscard²,Schmidt Thomas J.⁵,Wünsch Bernhard¹³^ORCID

Affiliation:

1. Institut für Pharmazeutische und Medizinische Chemie der Universität Münster Corrensstraße 48 48149 Münster Germany

2. Myocellular Electrophysiology and Molecular Biology Institute for Genetics of Heart Diseases (IfGH) Department of Cardiovascular Medicine University Hospital Münster 48149 Münster Germany

3. Cells-in-Motion Cluster of Excellence (EXC 1003—CiM) Westfälische Wilhelms-Universität Münster Münster Germany

4. Department of Chemistry and Applied Biosciences Institute of Pharmaceutical Sciences ETH Zürich Zürich Switzerland

5. Institut für Pharmazeutische Biologie und Phytochemie der Universität Münster Corrensstraße 48 48149 Münster Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201800214

Reference28 articles.

1. NMDA receptor function: subunit composition versus spatial distribution

2. Molecular basis of NMDA receptor functional diversity

3. Expression and role of ionotropic glutamate receptors in pancreatic islet cells

4. Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart

5. NMDA receptor subunits: function and pharmacology

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