Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain

Author:

Brindisi Margherita1,Borrelli Giuseppe1,Brogi Simone1,Grillo Alessandro1,Maramai Samuele1,Paolino Marco1,Benedusi Mascia2,Pecorelli Alessandra3,Valacchi Giuseppe23,Di Cesare Mannelli Lorenzo4,Ghelardini Carla4,Allarà Marco56,Ligresti Alessia5,Minetti Patrizia7,Campiani Giuseppe1,di Marzo Vincenzo58,Butini Stefania1ORCID,Gemma Sandra1

Affiliation:

1. European Research Centre for Drug Discovery and Development (NatSynDrugs); Department of Biotechnology, Chemistry, and Pharmacy (DoE 2018-2020); University of Siena; Via Aldo Moro 2 53100 Siena Italy

2. Department of Life Sciences and Biotechnology; University of Ferrara; Via Borsari 46 441212 Ferrara Italy

3. Department of Animal Science; North Carolina State University; NC Research Campus, PHHI Building, 600 Laureate Way Kannapolis NC 28081 USA

4. Department of Neuroscience, Psychology; Drug Research and Child Health; Section of Pharmacology and Toxicology (NEUROFARBA); University of Florence; Viale G. Pieraccini, 6 50139 Firenze Italy

5. Endocannabinoid Research Group; Institute of Biomolecular Chemistry; CNR; Via Campi Flegrei 80078 Pozzuoli (Napoli) Italy

6. EPITECH Group SpA; Via Egadi 7 20144 Milano Italy

7. Alfasigma; Via Pontina Km 30 400 00040 Pomezia Italy

8. Département de Médecine; Université Laval; 1050, Avenue de la Médecine Québec City QC G1V 0A6 Canada

Funder

Miur PRIN

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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