In silico Design, Synthesis, and Screening of Novel Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication-Reference-Cited by-同舟云学术

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In silico Design, Synthesis, and Screening of Novel Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication

Published:2014-03-11 Issue:5 Volume:9 Page:940-952
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Schroeder Marcus,Kolodzik Adrian,Pfaff Katharina,Priyadarshini Poornima,Krepstakies Marcel,Hauber Joachim,Rarey Matthias,Meier Chris

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201300481/fullpdf

Reference59 articles.

1. Antiretroviral Treatment of Adult HIV Infection

2. HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity

3. Safety and efficacy of once-daily nevirapine dosing: a multicohort study

4. Antiviral drug resistance

5. HIV drug development: the next 25 years

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1. Viral codon optimization on SARS‐CoV‐2 Spike boosts immunity in the development of COVID‐19 mRNA vaccines;Journal of Medical Virology;2023-10

2. eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon production;Frontiers in Cellular and Infection Microbiology;2022-07-27

3. Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation;Journal of Medicinal Chemistry;2021-09-02

4. Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney;Cell Death & Disease;2021-03-17

5. New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase;ACS Medicinal Chemistry Letters;2020-07-30

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