Methinylogation Approach in Chiral Pharmacophore Design: from Alkynyl- to Allenyl-carbinol Warheads against Tumor Cells-Reference-Cited by-同舟云学术

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Methinylogation Approach in Chiral Pharmacophore Design: from Alkynyl- to Allenyl-carbinol Warheads against Tumor Cells

Published:2018-07-23 Issue:16 Volume:13 Page:1711-1722
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Listunov Dymytrii¹,Joly Etienne²^ORCID,Duhayon Carine¹,Saffon-Merceron Nathalie³,Fabing Isabelle⁴,Génisson Yves⁴,Maraval Valérie¹,Chauvin Remi¹^ORCID

Affiliation:

1. LCC-CNRS; Université de Toulouse, CNRS, UPS; Toulouse France

2. UMR CNRS 5089, IPBS (Institut de Pharmacologie et de Biologie Structurale); 205 Route de Narbonne 31077 Toulouse cedex France

3. Université de Toulouse; UPS, ICT-FR 2599; 31062 Toulouse cedex 9 France

4. UMR CNRS 5068, LSPCMIB; Université de Toulouse, Université Paul Sabatier; 118 Route de Narbonne 31062 Toulouse cedex 9 France

Funder

CNRS

Toulouse IDEX Transversalité program 2015

The French Embassy in Kiev, Ukraine

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201800284/fullpdf

Reference64 articles.

1. Total synthesis of polyyne natural products

2. Polyacetylenes of Marine Origin: Chemistry and Bioactivity

3. Chiral alkynylcarbinols from marine sponges: asymmetric synthesis and biological relevance

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