Increased IL-6 Expression in Osteoclasts Is Necessary But Not Sufficient for the Development of Paget's Disease of Bone

Author:

Teramachi Jumpei1,Zhou Hua2,Subler Mark A3,Kitagawa Yukiko1,Galson Deborah L4,Dempster David W2,Windle Jolene J3,Kurihara Noriyoshi1,Roodman G David15

Affiliation:

1. Department of Medicine, Hematology Oncology; Indiana University; Indianapolis IN

2. Department of Pathology, College of Physician and Surgeons; Columbia University; New York NY

3. Department of Human and Molecular Genetics; Virginia Commonwealth University; Richmond VA

4. Department of Medicine, Hematology Oncology; University of Pittsburgh; Pittsburgh PA

5. Department of Medicine; Richard L. Roudebush VA Medical Center; Indianapolis IN

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Reference30 articles.

1. Paget's disease of bone;Hosking;Br Med J (Clin Res Ed).,1981

2. Metabolic consequences of bone turnover in Paget's disease of bone;Kanis;Clin Orthop.,1987

3. Paget's Disease of Bone

4. Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone;Roodman;J Clin Invest.,1992

5. Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease;Hoyland;J Bone Miner Res.,1994

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