Evaluation of differences between dual salt-pH gradient elution and mono gradient elution using a thermodynamic model: Simultaneous separation of six monoclonal antibody charge and size variants on preparative-scale ion exchange chromatographic resin-Reference-Cited by-同舟云学术

Evaluation of differences between dual salt-pH gradient elution and mono gradient elution using a thermodynamic model: Simultaneous separation of six monoclonal antibody charge and size variants on preparative-scale ion exchange chromatographic resin

Published:2018-03-25 Issue:4 Volume:34 Page:973-986
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Lee Yi Feng¹,Jöhnck Matthias²,Frech Christian¹^ORCID

Affiliation:

1. Institute of Biochemistry, Department of Biotechnology; University of Applied Sciences Mannheim; Mannheim Germany

2. Department of Process Solutions, Actives & Formulation; Merck KGaA; Darmstadt Germany

Publisher

Wiley

Subject

Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.2626/fullpdf

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4. Recent advances in large-scale production of monoclonal antibodies and related proteins;Shukla;Trends Biotech.,2010

5. What's fueling the biotech engine- 2010 to 2011;Aggarwal;Nat Biotech.,2011

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