A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs-Reference-Cited by-同舟云学术

A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs

Published:2021-09-28 Issue:5 Volume:110 Page:1293-1301
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharmacol Ther

Author:

Baier Vanessa¹,Clayton Olivia²,Nudischer Ramona²,Cordes Henrik¹,Schneider Annika R. P.¹,Thiel Christoph¹,Wittenberger Timo³,Moritz Wolfgang⁴,Blank Lars M.¹,Neumann Ulf P.⁵,Trautwein Christian⁶,Kelm Jens⁴,Schrooders Yannick⁷,Caiment Florian⁷,Gmuender Hans³,Roth Adrian⁴,Castell José V.⁸⁹,Kleinjans Jos⁷,Kuepfer Lars¹¹⁰

Affiliation:

1. Institute of Applied Microbiology RWTH Aachen Germany

2. Roche Pharmaceutical Research and Early Development Roche Innovation Center Basel Basel Switzerland

3. Genedata AG Basel Switzerland

4. InSphero AG Schlieren Switzerland

5. Department of Surgery University Hospital Aachen Aachen Germany

6. Department of Medicine III University Hospital RWTH Aachen Aachen Germany

7. Department of Toxicogenomics Maastricht University Maastricht Netherlands

8. Unidad de Hepatología Experimenta IIS Hospital Universitario La Fe Valencia Spain

9. Department of Bioquímica, Facultad de Medicina Universidad de Valencia, CIBEREHD‐ISCIII Valencia Spain

10. Institute of Systems Medicine with Focus on Organ Interaction University Hospital RWTH Aachen Aachen Germany

Funder