Affiliation:
1. Department of Orthopedics Trauma and Microsurgery Zhongnan Hospital of Wuhan University Wuhan China
Abstract
AbstractBackgroundSkin autografts have been broadly used to manage the skin and soft tissue defects. It is important for surgeons to assess the vitality of skin autografts via observing the angiogenesis. However, there is lack of reliable approach for giving the quantitative angiogenesis information on the skin autografts. Recently, photoacoustic microscopy imaging has attracted much attention based on its good performance in angiography.MethodsIn this study, we aim to monitor angiogenesis in skin autografts via PAM, and further verify its clinical potential for the early prediction of skin autografts clinical outcome.Results and ConclusionsThe results indicate that PAM is a feasible, precise, high‐resolution, noninvasive technique for the early prediction of necrosis of skin autografts via monitoring the angiogenesis, providing a promising tool for surgeons to use this surgical technology.
Funder
Fundamental Research Funds for the Central Universities
Zhongnan Hospital of Wuhan University
Subject
General Physics and Astronomy,General Engineering,General Biochemistry, Genetics and Molecular Biology,General Materials Science,General Chemistry