Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR‐engineered T cells-Reference-Cited by-同舟云学术

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Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR‐engineered T cells

Published:2021-06-21 Issue:8 Volume:51 Page:1992-2005
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Manfredi Francesco¹²^ORCID,Abbati Danilo¹,Cianciotti Beatrice Claudia¹,Stasi Lorena²,Potenza Alessia¹³,Ruggiero Eliana¹,Magnani Zulma¹,Carnevale Erica¹,Doglio Matteo¹²,Noviello Maddalena¹,Tassi Elena¹,Balestrieri Chiara¹,Buonanno Silvia¹,Clemente Francesca⁴,De Lalla Claudia⁵,Protti Maria Pia⁴,Mondino Anna⁶,Casorati Giulia⁵,Dellabona Paolo⁵^ORCID,Bonini Chiara¹²

Affiliation:

1. Experimental Hematology Unit San Raffaele Scientific Institute Milan Italy

2. Vita Salute San Raffaele University Milan Italy

3. School of Medicine and Surgery University of Milano–Bicocca Milan Italy

4. Tumor Immunology Unit San Raffaele Scientific Institute Milan Italy

5. Experimental Immunology Unit San Raffaele Scientific Institute Milan Italy

6. Lymphocyte Activation Unit San Raffaele Scientific Institute Milan Italy

Funder

European Commission

Ministero della Salute

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202049103

Reference49 articles.

1. TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals

2. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

3. NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma

4. Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS

5. Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

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2. Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus;Nature Communications;2024-03-27

3. TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells;Frontiers in Immunology;2024-02-29

4. Harnessing T cell exhaustion and trogocytosis to isolate patient-derived tumor-specific TCR;Science Advances;2023-12

5. Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells;Frontiers in Immunology;2023-10-04

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