Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols-Reference-Cited by-同舟云学术

Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols

Published:2023-05-04 Issue:24 Volume:135 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Xu Xiaomin¹,van Hengst Jacob M. A.¹^ORCID,Mao Yejia¹,Martinez Mireia²^ORCID,Roda Sergi²^ORCID,Floor Martin²^ORCID,Guallar Victor²³^ORCID,Paul Caroline E.¹^ORCID,Alcalde Miguel⁴^ORCID,Hollmann Frank¹^ORCID

Affiliation:

1. Department of Biotechnology Delft University of Technology van der Maasweg 9 2629HZ Delft (The Netherlands

2. Department of Life Sciences Barcelona Supercomputing Center Plaza Eusebi Güell 1-3 08034 Barcelona Spain

3. Institució Catalana de Recerca i Estudis Avançats Passeig de Lluís Companys, 23 08010 Barcelona Spain

4. Department of Biocatalysis Institute of Catalysis CSIC Madrid Spain

Abstract

AbstractA peroxygenase‐catalysed hydroxylation of organosilanes is reported. The recombinant peroxygenase from Agrocybe aegerita (AaeUPO) enabled efficient conversion of a broad range of silane starting materials in attractive productivities (up to 300 mM h−1), catalyst performance (up to 84 s−1 and more than 120 000 catalytic turnovers). Molecular modelling of the enzyme‐substrate interaction puts a basis for the mechanistic understanding of AaeUPO selectivity.

Funder

European Commission

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202302844

Reference58 articles.

2. Catalytic Synthesis of Silanols from Hydrosilanes and Applications

3. Recent Developments in the Synthesis and Structure of Organosilanols

4. Procedures for the preparation of silanols