Synthese und Biologische Untersuchungen von C(13)/C(13′)‐Bis(desmethyl)disorazol Z**-Reference-Cited by-同舟云学术

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Synthese und Biologische Untersuchungen von C(13)/C(13′)‐Bis(desmethyl)disorazol Z**

Published:2022-12-20 Issue:5 Volume:135 Page:
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Bold Christian Paul¹^ORCID,Lucena‐Agell Daniel²^ORCID,Oliva María Ángela²^ORCID,Díaz José Fernando²^ORCID,Altmann Karl‐Heinz¹^ORCID

Affiliation:

1. Departement Chemie und Angewandte Biowissenschaften Institut für Pharmazeutische Wissenschaften ETH Zürich Vladimir-Prelog-Weg 4 8093 Zürich Schweiz

2. Centro de Investigaciones Biológicas Margarita Salas Consejo Superior de Investigaciones Científicas Ramiro de Maeztu 9 28040 Madrid Spanien

Funder

Ministerio de Ciencia e Innovación

Fundación Tatiana Pérez de Guzmán el Bueno

Eidgenössische Technische Hochschule Zürich

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202212190

Reference88 articles.

1. Antibiotics from Gliding Bacteria, LIX. Disorazoles, Highly Cytotoxic Metabolites from the Sorangicin-Producing BacteriumSorangium Cellulosum, Strain So ce12

2. Antibiotics from gliding bacteria. No.62. Disorazol A, an Efflcient Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria.

3. Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells

4. Microtubule Binding and Disruption and Induction of Premature Senescence by Disorazole C1

5. Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues

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