From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein‐Templated Synthesis-Reference-Cited by-同舟云学术

From Kinase Inhibitors to Multitarget Ligands as Powerful Drug Leads for Alzheimer's Disease using Protein‐Templated Synthesis

Published:2021-07-26 Issue:35 Volume:133 Page:19493-19503
ISSN:0044-8249
Container-title:Angewandte Chemie
language:en
Short-container-title:Angewandte Chemie

Author:

Nozal Vanesa¹,García‐Rubia Alfonso¹²,Cuevas Eva P.¹,Pérez Concepción³,Tosat‐Bitrián Carlota¹,Bartolomé Fernando⁴,Carro Eva⁴,Ramírez David⁵,Palomo Valle¹²^ORCID,Martínez Ana¹²^ORCID

Affiliation:

1. Structural and Chemical Biology Department Centro de Investigaciones Biológicas-CSIC Ramiro de Maeztu 9 28040 Madrid Spain

2. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED) Instituto de Salud Carlos III 28031 Madrid Spain

3. Instituto de Química Médica-CSIC) Juan de la Cierva 3 28006 Madrid Spain

4. Hospital Universitario 12 de Octubre Research Institute (imas12) Group of Neurodegenerative Diseases Juan de la Cierva 3 28006 Madrid Spain

5. Instituto de Ciencias Biomédicas Universidad Autónoma de Chile Llano Subercaseaux 2801—piso 6 Santiago Chile

Funder

Ministerio de Ciencia, Innovación y Universidades

Instituto de Salud Carlos III

Ministerio de Educación, Cultura y Deporte

Consejo Nacional de Innovación, Ciencia y Tecnología

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.202106295

Reference40 articles.

1. Polypharmacology in a Single Drug: Multitarget Drugs

2. Multitarget therapeutic strategies for Alzheimer’s disease

3. A perspective on multi‐target drug discovery and design for complex diseases

4. The current status of pharmacotherapy for the treatment of Parkinson’s disease: transition from single-target to multitarget therapy

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