Simple and reliable method to simultaneously determine urinary 1‐ and 2‐naphthol using in situ derivatization and gas chromatography‐mass spectrometry for biological monitoring of naphthalene exposure in occupational health practice

Author:

Takeuchi Akito1ORCID,Nakamura Sadao2,Namera Akira3,Kondo Tomoaki4,Onuki Hiroyuki5,Yamamoto Shinobu6ORCID,Okamura Shingo1,Nishinoiri Osamu1,Endo Yoko7,Miyauchi Hiroyuki6,Endo Ginji1

Affiliation:

1. Osaka Occupational Health Service Center Japan Industrial Safety and Health Association Osaka Japan

2. Agilent Technologies Japan, Ltd. Tokyo Japan

3. Department of Forensic Medicine Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan

4. Global Application Development Center Analytical & Measuring Instruments Division Shimadzu Corporation Kyoto Japan

5. College of Science Rikkyo University Tokyo Japan

6. Department of Environmental Measurement and Control School of Health Sciences University of Occupational and Environmental Health Kitakyushu Japan

7. Endo Occupational Health Consultant Office Osaka Japan

Publisher

Wiley

Subject

Public Health, Environmental and Occupational Health

Reference22 articles.

1. Japan Ministry of Health Labour and Welfare.Amendments to the Ordinance on Prevention of Hazards Due to Specified Chemical Substances Working Environment Measurement Standards and others in November 2015 Addition of regulations on naphthalene and refractory ceramic fibers (RCF).https://www.mhlw.go.jp/stf/seisakunitsuite/bunya/0000099121.html. Published October 2015. Accessed January 18 2020 (in Japanese)

2. Some traditional herbal medicines, some mycotoxins, naphthalene and styrene;IARC;IARC Monogr Eval Carcinog Risks Hum,2002

3. Recommendation of occupational exposure limits (2019–2020)

4. Deutsche Forschungsgemeinschaft.Naphthalene MAK Value Documentation.2012.https://doi.org/10.1002/3527600418.mb9120e0027. Published March 2013. Accessed January 18 2020

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