The Influence of Lipids on Stereoselective Pharmacokinetics of Halofantrine: Important Implications in Food‐Effect Studies Involving Drugs That Bind to Lipoproteins-Reference-Cited by-同舟云学术

The Influence of Lipids on Stereoselective Pharmacokinetics of Halofantrine: Important Implications in Food‐Effect Studies Involving Drugs That Bind to Lipoproteins

Published:2002-08 Issue:8 Volume:91 Page:1817-1826
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Brocks Dion R.,Wasan Kishor M.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference26 articles.

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2. A physicochemical basis for the effect of food on the absolute oral bioavailability of halofantrine;Humberstone;J Pharm Sci,1996

3. Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state;Humberstone;J Pharm Sci,1998

4. The antimalarial drug halofantrine is bound mainly to low and high density lipoproteins in human serum;Cenni;Br J Clin Pharmacol,1995

5. Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid;McIntosh;J Pharm Sci,1999

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