Thermodynamics in Drug Discovery
Author:
Affiliation:
1. Business Development-MicroCal; Malvern Instruments; Northampton MA USA
2. Scientific Marketing Biosciences; Malvern Instruments; Stockholm Sweden
3. Structure and Biophysics, Discovery Sciences; AstraZeneca; Cambridge UK
Publisher
John Wiley & Sons, Ltd
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/9781119099512.ch2/fullpdf
Reference52 articles.
1. Ligand binding thermodynamics in drug discovery: still a hot tip?;Geschwindner;Journal of Medicinal Chemistry,2015
2. Do enthalpy and entropy distinguish first in class from best in class?;Freire;Drug Discovery Today,2008
3. Adaptive inhibitors of the HIV-1 protease;Ohtaka;Progress in Biophysics and Molecular Biology,2005
4. Thermodynamics guided lead discovery and optimization;Ferenczy;Drug Discovery Today,2010
5. The influence of drug-like concepts on decision-making in medicinal chemistry;Leeson;Nature Reviews Drug Discovery,2007
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