Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition ( EPIC ) cohort

Author:

Christakoudi Sofia12ORCID,Pagoni Panagiota345,Ferrari Pietro6ORCID,Cross Amanda J.1,Tzoulaki Ioanna13,Muller David C.1,Weiderpass Elisabete6,Freisling Heinz6,Murphy Neil6ORCID,Dossus Laure6,Turzanski Fortner Renee7,Agudo Antonio8,Overvad Kim910,Perez‐Cornago Aurora11,Key Timothy J.11,Brennan Paul6,Johansson Mattias6,Tjønneland Anne12,Halkjær Jytte12,Boutron‐Ruault Marie‐Christine13ORCID,Artaud Fanny13,Severi Gianluca1314ORCID,Kaaks Rudolf7,Schulze Matthias B.1516,Bergmann Manuela M.17,Masala Giovanna18,Grioni Sara19,Simeon Vittorio20,Tumino Rosario21,Sacerdote Carlotta22ORCID,Skeie Guri23,Rylander Charlotta23,Borch Kristin Benjaminsen23,Quirós J. Ramón24,Rodriguez‐Barranco Miguel252627,Chirlaque Maria‐Dolores272829,Ardanaz Eva273031,Amiano Pilar2732,Drake Isabel33ORCID,Stocks Tanja34,Häggström Christel3536ORCID,Harlid Sophia37,Ellingjord‐Dale Merete1,Riboli Elio1,Tsilidis Konstantinos K.13

Affiliation:

1. Department of Epidemiology and Biostatistics, School of Public Health Imperial College London London UK

2. MRC Centre for Transplantation King's College London London UK

3. Department of Hygiene and Epidemiology University of Ioannina School of Medicine Ioannina Greece

4. MRC Integrative Epidemiology Unit University of Bristol Bristol UK

5. Population Health Sciences, Bristol Medical School University of Bristol Bristol UK

6. International Agency for Research on Cancer World Health Organization Lyon France

7. Division of Cancer Epidemiology German Cancer Research Center (DKFZ) Heidelberg Germany

8. Unit of Nutrition and Cancer. Cancer Epidemiology Research Program Catalan Institute of Oncology‐IDIBELL. L'Hospitalet de Llobregat Barcelona Spain

9. Department of Public Health Aarhus University Aarhus Denmark

10. Department of Cardiology Aalborg University Hospital Aalborg Denmark

11. Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford Oxford UK

12. Danish Cancer Society Research Center Copenhagen Denmark

13. Université Paris‐Saclay, UVSQ, Univ. Paris‐Sud, Inserm, Équipe "Exposome, Hérédité, Cancer et Santé", CESP, Gustave Roussy Villejuif France

14. Department of Statistics, Computer Science, and Applications "G. Parenti" (DISIA) University of Florence Florence Italy

15. Department of Molecular Epidemiology German Institute of Human Nutrition Potsdam‐Rehbruecke Nuthetal Germany

16. Institute of Nutrition Science University of Potsdam Nuthetal Germany

17. Department of Epidemiology German Institute of Human Nutrition Potsdam‐Rehbrücke (DIfE) Nuthetal Germany

18. Cancer Risk Factors and Life‐Style Epidemiology Unit, Institute for Cancer Research Prevention and Clinical Network – ISPRO Florence Italy

19. Epidemiology and Prevention Unit Fondazione IRCCS Istituto Nazionale dei Tumori di Milano Milan Italy

20. Dep. of Mental Physical Health and Preventive Medicine University "L.Vanvitelli" Naples Italy

21. Cancer Registry and Histopathology Department Provincial Health Authority (ASP) Ragusa Italy

22. Unit of Cancer Epidemiology Città della Salute e della Scienza University‐Hospital and Center for Cancer Prevention (CPO) Turin Italy

23. Department of Community Medicine UiT The Arctic university of Norway Tromsø Norway

24. Public Health Directorate Asturias Spain

25. Escuela Andaluza de Salud Pública (EASP) Granada Spain

26. Instituto de Investigación Biosanitaria ibs.GRANADA Granada Spain

27. Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP) Madrid Spain

28. Department of Epidemiology Regional Health Council, IMIB‐Arrixaca Murcia Spain

29. Department of Health and Social Sciences Universidad de Murcia Murcia Spain

30. Navarra Public Health Institute Pamplona Spain

31. IdiSNA, Navarra Institute for Health Research Pamplona Spain

32. Public Health Division of Gipuzkoa BioDonostia Researach Institute San Sebastian Spain

33. Department of Clinical Sciences in Malmö Lund University Malmö Sweden

34. Department of Clinical Sciences Lund Lund University Lund Sweden

35. Department of Biobank Research Umeå University Umeå Sweden

36. Department of Surgical Science Uppsala University Uppsala Sweden

37. Department of Radiation Sciences Umeå University Umeå Sweden

Funder

Associazione Italiana per la Ricerca sul Cancro

Bundesministerium für Bildung und Forschung

Cancer Research UK

Cancerfonden

Centre International de Recherche sur le Cancer

Deutsche Krebshilfe

Deutsches Krebsforschungszentrum

Directorate-General for Health and Consumers

Institut Gustave-Roussy

Institut National de la Santé et de la Recherche Médicale

Kræftens Bekæmpelse

Ligue Contre le Cancer

Medical Research Council Canada

Mutuelle Générale de l'Education Nationale

Vetenskapsrådet

World Cancer Research Fund

European Commission

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference52 articles.

1. Adiposity and cancer at major anatomical sites: umbrella review of the literature

2. Body Fatness and Cancer — Viewpoint of the IARC Working Group

3. World Cancer Research Fund Continuous Update Project.Third expert report: Body fatness and weight gain and the risk of cancer;2018.https://www.wcrf.org/sites/default/files/Body-fatness-and-weight-gain_0.pdf. Accessed September 1 2020.

4. Rates of weight change for black and white Americans over a twenty year period

5. Age-related differences in fat-free mass, skeletal muscle, body cell mass and fat mass between 18 and 94 years

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