Design and preparation of hydrogel microspheres for spinal cord injury repair

Author:

Zheng Jian12,Chen Ruilin12,Hao Jie2,Yang Yang3,Xu Shaohu12,Zhang Feiyu12,Zhang Feng2,Yao Yu2ORCID

Affiliation:

1. Medical School of Nantong University Nantong Jiangsu Province China

2. Department of Orthopedics Affiliated Hospital of Nantong University Nantong Jiangsu Province China

3. Department of Emergency Surgery Affiliated Hospital of Nantong University Nantong Jiangsu China

Abstract

AbstractA severe disorder known as spinal cord damage causes both motor and sensory impairment in the limbs, significantly reducing the patients' quality of life. After a spinal cord injury, functional recovery and therapy have emerged as critical concerns. Hydrogel microspheres have garnered a lot of interest lately because of their enormous promise in the field of spinal cord injury rehabilitation. The material classification of hydrogel microspheres (natural and synthetic macromolecule polymers) and their synthesis methods are examined in this work. This work also covers the introduction of several kinds of hydrogel microspheres and their use as carriers in the realm of treating spinal cord injuries. Lastly, the study reviews the future prospects for hydrogel microspheres and highlights their limitations and problems. This paper can offer feasible ideas for researchers to advance the application of hydrogel microspheres in the field of spinal cord injury.

Publisher

Wiley

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