The Effect of Post‐Treatment Combined Lifestyle Interventions on Quality of Life in Colorectal Cancer Patients – A Systematic Review

Author:

Gielen Anke H. C.12ORCID,Thomassen Britt J. M.12,Bult Tim J.3,Melenhorst Jarno124,Kimman Merel L.5,Breukink Stephanie O.124

Affiliation:

1. Department of Surgery Maastricht University Medical Centre Maastricht The Netherlands

2. School of Nutrition and Translational Research in Metabolism (NUTRIM) Maastricht University Maastricht The Netherlands

3. Faculty of Health Medicine and Life Sciences Maastricht University Maastricht The Netherlands

4. GROW School for Oncology and Developmental Biology Maastricht The Netherlands

5. Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA) Maastricht University Medical Centre Maastricht The Netherlands

Abstract

ABSTRACTBackgroundColorectal cancer is identified as a lifestyle‐related type of cancer. There is an increasing emphasis on lifestyle interventions targeting pivotal lifestyle factors such as excess weight, cigarette smoking, alcohol consumption, poor diet and physical inactivity as primary and tertiary prevention. Furthermore, modifying these lifestyle factors has the potential to improve quality of life for cancer patients. We aim to identify, appraise and synthesise the available evidence regarding the effect of combined lifestyle interventions on quality of life in colorectal cancer survivors.MethodsPubmed, Ovid Embase and the Cochrane Library were searched for studies reporting on quality of life in post‐treatment colorectal cancer patients. The systematic literature search was performed according to the Preferred Reporting Items for systematic reviews and meta‐analysis (PRISMA) guidelines.ResultsFive articles reporting on 719 individual patients were included. Two studies reported significantly better results in (cancer‐specific) quality‐of‐life questionnaires for patients after combined lifestyle interventions.ConclusionWe conclude that there is some evidence that combined lifestyle interventions could have beneficial effects on the quality of life of colorectal cancer survivors. Future randomised controlled trials reporting on quality of life of combined lifestyle interventions in colorectal cancer survivors are warranted.

Publisher

Wiley

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