Hydroxychloroquine and Risk of Long QT Syndrome in Rheumatoid Arthritis: A Veterans Cohort Study With Nineteen‐Year Follow‐up

Author:

Quiñones Mercedes E.1,Joseph Joyce K.2,Dowell Sharon1,Moore Hans J.3,Karasik Pamela E.4,Fonarow Gregg C.5,Fletcher Ross D.2,Cheng Yan6,Zeng‐Treitler Qing6,Arundel Cherinne7,Liappis Angelike P.7,Sheriff Helen M.6,Zhang Sijian2,Taub Daniel D.6,Heimall Michael S.2,Faselis Charles7,Kerr Gail S.8,Ahmed Ali9ORCID

Affiliation:

1. Veterans Affairs Medical Center, and Howard University Washington DC

2. Veterans Affairs Medical Center Washington DC

3. Veterans Affairs Medical Center, Georgetown University, George Washington University, Uniformed Services University, and US Department of Veterans Affairs Washington DC

4. Veterans Affairs Medical Center, Georgetown University, George Washington University, and Uniformed Services University Washington DC

5. University of California Los Angeles CA

6. Veterans Affairs Medical Center and George Washington University Washington DC

7. Veterans Affairs Medical Center, George Washington University, and Uniformed Services University Washington DC

8. Veterans Affairs Medical Center, Howard University, and Georgetown University Washington DC

9. Veterans Affairs Medical Center, Georgetown University, and George Washington University Washington DC

Funder

U.S. Department of Veterans Affairs

Publisher

Wiley

Subject

Rheumatology

Reference42 articles.

1. Plaquenil® hydroxychloroquine sulfate tablets, USP;The Food and Drug Administration (FDA);Full prescribing information.,2021

2. Considerations for Drug Interactions on QTc Interval in Exploratory COVID-19 Treatment

3. QTc-interval prolongation and increased risk of sudden cardiac death associated with hydroxychloroquine

4. World Health Organization (WHO) Malaria Policy Advisory Committee.The cardiotoxicity of antimalarials.2017. URL:https://www.who.int/publications/m/item/meeting‐report‐of‐the‐evidence‐review‐group‐on‐the‐cardiotoxicity‐of‐antimalarials.

5. American College of Cardiology.Ventricular arrhythmia risk due to hydroxychloroquine‐azithromycin treatment for COVID‐19.2020. URL:https://www.acc.org/latest-in-cardiology/articles/2020/03/27/14/00/ventricular-arrhythmia-risk-due-to-hydroxychloroquine-azithromycin-treatment-for-covid-19.

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