How the signal-to-noise ratio influences hyperpolarized 13 C dynamic MRS data fitting and parameter estimation

Author:

Santarelli Maria Filomena12,Positano Vincenzo21,Giovannetti Giulio1,Frijia Francesca2,Menichetti Luca12,Ardenkjaer-Larsen Jan-Henrik34,De Marchi Daniele2,Lionetti Vincenzo5,Aquaro Giovanni2,Lombardi Massimo2,Landini Luigi612

Affiliation:

1. Institute of Clinical Physiology; National Research Council; Pisa Italy

2. Fondazione G. Monasterio CNR; Regione Toscana; Pisa Italy

3. GE Healthcare Park Alle 295, Broendby; Denmark

4. Department of Electrical Engineering; The Technical University of Denmark; Lyngby Denmark

5. Laboratory of Medical Science, Institute of Life Sciences; Scuola Superiore Sant'Anna; Pisa Italy

6. Department of Information Engineering: EIT; University of Pisa; Pisa Italy

Publisher

Wiley

Subject

Spectroscopy,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference43 articles.

1. In vivo13C NMR spectroscopy and metabolic modelling in the brain: a practical perspective;Henry;Magn. Res. Imaging,2006

2. In vivo carbon-13 nuclear magnetic resonance studies of heart metabolism;Neurohr;Proc. Natl. Acad. Sci. USA,1983

3. Metabolic compartmentation of lactate in the glucose-perfused rat heart;Chatham;Am. J. Physiol.,1996

4. Two-compartment model for determination of glycolytic rates of solid tumors by in vivo 13C NMR spectroscopy;Artemov;NMR Biomed.,1998

5. Clinical experience with 13C MRS in vivo;Ross;NMR Biomed.,2003

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