Development and validation of LC-MS/MS method for the estimation ofβ-hydroxy-β-methylbutyrate in rat plasma and its application to pharmacokinetic studies-Reference-Cited by-同舟云学术

Development and validation of LC-MS/MS method for the estimation ofβ-hydroxy-β-methylbutyrate in rat plasma and its application to pharmacokinetic studies

Published:2012-05-24 Issue:2 Volume:27 Page:142-147
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Deshpande Parag¹,Jie Zhang²,Subbarayan Ramesh¹,Mamidi Vijay Kumar¹,Chunduri Raja Haranadha Babu¹,Das Tapas²,Shreeram Sathyavageeswaran²

Affiliation:

1. Syngene International Limited. Biocon Park; Jigani Link Road; Bangalore; 560099; India

2. Abbott Nutrition Research and Development; 20 Biopolis Way; Singapore; 138668

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference10 articles.

1. β-hydroxy-β-methylbutyrate (HMB) attenuates muscle and body weight loss in experimental cancer cachexia;Aversa;International Journal of Oncology,2011

2. Management of muscle wasting in cancer-associated cachexia: understanding gained from experimental studies;Baracos;Cancer,2001

3. Signaling pathways initiated by β-hydroxy-β-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli;Eley;American Journal of Physiology - Endocrinology and Metabolism,2007

4. β-Hydroxy-β-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways;Kornasio;Biochimica et Biophysica Acta,2009

5. Analysis of β-Hydroxy-β-methylbutyrate in plasma by gas chromatography and mass spectrometry;Nissen;Analytical Biochemistry,1990

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