Advances in inline quantification of co-eluting proteins in chromatography: Process-data-based model calibration and application towards real-life separation issues
Author:
Affiliation:
1. Karlsruhe Institute of Technology; Engler-Bunte-Ring 1, 76131 Karlsruhe Germany
2. CSL Behring Australia; Broadmeadows VIC Australia
Funder
Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Reference29 articles.
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2. A sub-two minutes method for monoclonal antibody-aggregate quantification using parallel interlaced size exclusion high performance liquid chromatography;Diederich;J Chromatogr A,2011
3. Chemistry and metabolism of macromolecules: Changes in ultraviolet absorption produced by alteration of protein conformation;Donovan;J Biol Chem,1969
4. Real-time control of purified product collection during chromatography of recombinant human insulin-like growth factor-I using an on-line assay;Fahrner;J Chromatogr A,1998
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