Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window-Reference-Cited by-同舟云学术

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Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window

Published:2015-05-19 Issue:1 Volume:98 Page:76-86
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin. Pharmacol. Ther.

Author:

Coutant DE¹,Kulanthaivel P¹,Turner PK²,Bell RL²,Baldwin J²,Wijayawardana SR³,Pitou C²,Hall SD¹

Affiliation:

1. Department of Drug Disposition; Eli Lilly and Company; Indianapolis Indiana USA

2. Pharmacokinetics and Pharmacodynamics; Eli Lilly and Company; Indianapolis Indiana USA

3. Department of Statistics-Oncology; Eli Lilly and Company; Indianapolis Indiana USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference66 articles.

1. Symposium report: Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer;Morgan;Drug. Metab. Disp.,2008

2. Cancer, inflammation, and therapy: effects on cytochrome P450-mediated drug metabolism and implications for novel immunotherapeutic agents;Harvey;Clin. Pharm. Ther.,2014

3. Inflammation and CYP3A4-mediated drug metabolism in advanced cancer: impact and implications for chemotherapeutic drug dosing;Kacevska;Expert Opin. Drug Metab. Toxicol.,2008

4. Inflammation-mediated changes in drug transporter expression/activity: implications for therapeutic drug response;Cressman;Expert Rev. Clin. Pharmacol.,2012

5. Systemic inflammation and prediction of chemotherapy outcomes in patients receiving docetaxel for advanced cancer;Chua;Support Care Cancer.,2011

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