Metastatic prostate cancer-associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6

Author:

Jiang Xianhan1,Huang Yiqiao1,Liang Xue1,Jiang Funeng2,He Yongzhong1,Li Tian1,Xu Guibin1,Zhao Haibo1,Yang Weiqing1,Jiang Ganggang1,Su Zhengming1,Jiang Lingke1,Liu Leyuan134ORCID

Affiliation:

1. Department of Urology; The Fifth Affiliated Hospital of Guangzhou Medical University; Guangzhou China

2. Department of Urology; Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics; Guangzhou First People's Hospital; Guangzhou Medical University; Guangzhou China

3. Center for Translational Cancer Research, Institute of Biosciences and Technology; Texas A&M University; Houston Texas

4. Department of Molecular and Cellular Medicine, College of Medicine; Texas A&M University; College Station Texas

Funder

NIH Clinical Center

National Natural Science Foundation of China

Guangzhou Municipal Science and Technology Project

Publisher

Wiley

Subject

Urology,Oncology

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