The orally active pterocarpanquinone LQB-118 exhibits cytotoxicity in prostate cancer cell and tumor models through cellular redox stress-Reference-Cited by-同舟云学术

The orally active pterocarpanquinone LQB-118 exhibits cytotoxicity in prostate cancer cell and tumor models through cellular redox stress

Published:2017-11-06 Issue:2 Volume:78 Page:140-151
ISSN:0270-4137
Container-title:The Prostate
language:en
Short-container-title:Prostate

Author:

Martino Thiago¹²,Kudrolli Tarana A.²,Kumar Binod²,Salviano Isis³,Mencalha André³,Coelho Marsen Garcia P.¹,Justo Graça¹,Costa Paulo R. Ribeiro⁴,Sabino Kátia C. Carvalho¹^ORCID,Lupold Shawn E.²

Affiliation:

1. Department of Biochemistry; LIA-BPPN; State University of Rio de Janeiro; Rio de Janeiro Brazil

2. Department of Urology; The James Brady Urological Institute; Johns Hopkins University School of Medicine; Baltimore Maryland

3. Department of Biophysics and Biometry; Laboratory of Cancer Biology; State University of Rio de Janeiro; Rio de Janeiro Brazil

4. IPPN, Laboratory of Chemistry Bioorganic; Federal University of Rio de Janeiro; Rio de Janeiro Brazil

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Foundation for the National Institutes of Health

Publisher

Wiley

Subject

Urology,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/pros.23455/fullpdf

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4. The pterocarpanquinone LQB-118 induces apoptosis in tumor cells through the intrinsic pathway and the endoplasmatic reticulum stress;de Sa Bacelar;Anticancer Drugs,2013

5. LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1, 4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells;Maia;Invest New Drugs,2011

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