High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 2. An example of how unexpected dissociation behaviour could preclude correct assignment of sites of metabolism-Reference-Cited by-同舟云学术

High‐throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 2. An example of how unexpected dissociation behaviour could preclude correct assignment of sites of metabolism

Published:2009-07-15 Issue:13 Volume:23 Page:2017-2025
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Holman Stephen W.,Wright Patricia,Langley G. John

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference19 articles.

1. Analytical strategies for identifying drug metabolites

2. Application of semi-automated metabolite identification software in the drug discovery process for rapid identification of metabolites and the cytochrome P450 enzymes responsible for their formation

3. Role of pharmacologically active metabolites in drug discovery and development

4. The identification ofin vitro metabolites of CKD-732 by liquid chromatography/tandem mass spectrometry

5. Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry

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