AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations

Author:

Cho Eunnara12ORCID,Allemang Ashley3ORCID,Audebert Marc4ORCID,Chauhan Vinita5,Dertinger Stephen6,Hendriks Giel7,Luijten Mirjam8ORCID,Marchetti Francesco12ORCID,Minocherhomji Sheroy9,Pfuhler Stefan3,Roberts Daniel J.10,Trenz Kristina11,Yauk Carole L.1212ORCID

Affiliation:

1. Environmental Health Science and Research Bureau Health Canada Ottawa Ontario Canada

2. Department of Biology Carleton University Ottawa Ontario Canada

3. The Procter & Gamble Company Mason Ohio USA

4. Toxalim, UMR1331 INRAE Toulouse France

5. Consumer and Clinical Radiation Protection Bureau Health Canada Ottawa Ontario Canada

6. Litron Laboratories Rochester New York USA

7. Toxys Leiden The Netherlands

8. Centre for Health Protection National Institute for Public Health and the Environment (RIVM) Bilthoven The Netherlands

9. Amgen Research, Translational Safety and Bioanalytical Sciences Amgen Inc. Thousand Oaks California USA

10. Charles River Laboratories Skokie Illinois USA

11. Ingelheim Pharma GmbH & Co.KG Biberach Germany

12. Department of Biology University of Ottawa Ottawa Ontario Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology

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