Off‐Label Use of Ketamine: A Challenging Drug Treatment Delivery Model With an Inherently Unfavorable Risk‐Benefit Profile

Author:

Pai Sudhakar M.ORCID,Gries Jean‐Michel,

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference16 articles.

1. Ten Common Questions (and Their Answers) About Off-label Drug Use

2. US Food and Drug Administration. “Off‐label” and investigational use of marketed drugs biologics and medical devices. Guidance for institutional review boards and clinical investigators.https://www.fda.gov/regulatory-information/search-fda-guidance-documents/label-and-investigational-use-marketed-drugs-biologics-and-medical-devices. Published January 1998. Accessed July 27 2021.

3. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

4. KETALAR (ketamine hydrochloride) drug label.https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/016812Orig1s046lbl.pdf. Published2020. Accessed July 27 2021.

5. Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

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