Translational Pharmacokinetic/Pharmacodynamic Modeling of Tumor Growth Inhibition Supports Dose-Range Selection of the Anti-PD-1 Antibody Pembrolizumab
Author:
Affiliation:
1. Merck & Co., Inc.; Rahway New Jersey USA
Publisher
Wiley
Subject
Pharmacology (medical),Modelling and Simulation
Reference26 articles.
1. Mechanisms of immune evasion by tumors;Drake;Adv. Immunol.,2006
2. The blockade of immune checkpoints in cancer immunotherapy;Pardoll;Nat. Rev. Cancer,2012
3. Tumor immunotherapy directed at PD-1;Ribas;N. Engl. J. Med.,2012
4. Immune regulation of cancer;Disis;J. Clin. Oncol.,2010
5. Improved survival with ipilimumab in patients with metastatic melanoma;Hodi;N. Engl. J. Med.,2010
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