Translational Pharmacometric Evaluation of Typical Antibiotic Broad-Spectrum Combination Therapies AgainstStaphylococcus AureusExploitingIn VitroInformation

Author:

Wicha SG1,Huisinga W2,Kloft C1

Affiliation:

1. Department of Clinical Pharmacy and Biochemistry; Institute of Pharmacy, Freie Universitaet Berlin; Berlin Germany

2. Institute of Mathematics, University of Potsdam; Potsdam-Golm Germany

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Reference47 articles.

1. WHO Antimicrobial Resistance Global Report on Surveillance http://www.who.int/drugresistance/documents/surveillancereport/en 2014

2. Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study;Wunderink;Clin. Infect. Dis.,2012

3. 2012 http://www.ecdc.europa.eu/en/healthtopics/antimicrobial_resistance/database/Pages/table_reports.aspx

4. Pharmacokinetic-pharmacodynamic modeling of antibacterial drugs;Nielsen;Pharmacol. Rev.,2013

5. Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization;Nielsen;Antimicrob. Agents Chemother.,2011

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