Identification of Polyproline II Regions Derived From the Proline-Rich Nuclear Receptor Coactivators PNRC and PNRC2: New Insights for ERα Coactivator Interactions

Author:

Byrne C.12,Miclet E.1,Broutin I.3,Gallo D.4,Pelekanou V.56,Kampa M.6,Castanas E.6,Leclercq G.7,Jacquot Y.12

Affiliation:

1. Laboratoire des BioMolécules (LBM), CNRS - UMR 7203; Ecole Normale Supérieure / Université Pierre et Marie Curie 24, rue Lhomond, 75231; Paris Cedex 05 France

2. Fondation Pierre-Gilles de Gennes pour la Recherche, 29, rue d'Ulm, 75005; Paris France

3. Laboratoire de Cristallographie et RMN biologiques, CNRS - UMR 8015; Université Paris-Descartes, 4, avenue de l'Observatoire, 75006; Paris France

4. Service des Industries Biochimiques; Institut Meurice, avenue Emile Gryzon 1; Brussels Belgium

5. Laboratory of Pathology; University of Crete, School of Medicine; Heraklion, Greece

6. Laboratory of Experimental Endocrinology; University of Crete, School of Medicine; P.O. Box 2208, Heraklion 71003, Greece

7. Laboratoire J.-C. Heuson de Cancérologie Mammaire; Université Libre de Bruxelles (U.L.B.), Institut Jules Bordet, rue Héger-Bordet 1; Brussels 1000 Belgium

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Pharmacology,Catalysis,Analytical Chemistry

Reference91 articles.

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3. Development of peptide antagonists that target estrogen receptor β-coactivator interactions;Hall;Mol Endocrinol,2000

4. Design, synthesis, and in vitro biological evaluation of small molecule inhibitors of estrogen receptor α coactivator binding;Rodriguez;J Med Chem,2004

5. Peptides targeting estrogen receptor alpha -potential applications for breast cancer treatment;Leclercq;Curr Pharm Design,2011

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