Complexity and challenges in defining myeloid-derived suppressor cells

Author:

Damuzzo Vera1,Pinton Laura1,Desantis Giacomo2,Solito Samantha1,Marigo Ilaria2,Bronte Vincenzo3,Mandruzzato Susanna12

Affiliation:

1. Section of Oncology and Immunology; Department of Surgery; Oncology and Gastroenterology; University of Padova; Padova Italy

2. Veneto Institute of Oncology IOV-IRCCS; Padova Italy

3. Section of Immunology; Department of Pathology; Verona University Hospital; Verona Italy

Funder

Fondazione Cassa di Risparmio di Verona, Vicenza, Belluno e Ancona

Italian Association for Cancer Research (AIRC)

Italian Ministry of Education, Universities, and Research

Italian Ministry of Health

Publisher

Wiley

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference125 articles.

1. Coordinated regulation of myeloid cells by tumours;Gabrilovich;Nat Rev Immunol,2012

2. Highlights on molecular mechanisms of MDSC-mediated immune suppression: Paving the way for new working hypotheses;Solito;Immunol Invest,2012

3. Apoptotic death of CD8+ T lymphocytes after immunization: Induction of a suppressive population of Mac-1+/Gr-1+ cells;Bronte;J Immunol,1998

4. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation;Bronte;J Immunol,1999

5. Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species;Kusmartsev;J Immunol,2004

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