Role of receptor occupancy assays by flow cytometry in drug development-Reference-Cited by-同舟云学术

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Role of receptor occupancy assays by flow cytometry in drug development

Published:2016-02-16 Issue:2 Volume:90 Page:110-116
ISSN:1552-4949
Container-title:Cytometry Part B: Clinical Cytometry
language:en
Short-container-title:Cytometry

Author:

Stewart Jennifer J.¹,Green Cherie L.²,Jones Nicholas³,Liang Meina⁴,Xu Yuanxin⁵,Wilkins Danice E. C.⁶,Moulard Maxime⁷,Czechowska Kamila⁸,Lanham David⁹,McCloskey Thomas W.¹⁰,Ferbas John²,van der Strate Barry. W. A.¹¹,Högerkorp Carl-Magnus¹²,Wyant Timothy¹³,Lackey Alan³,Litwin Virginia¹⁴

Affiliation:

1. Flow Contract Site Laboratory, LLC; Bothell Washington 98012

2. Amgen, Inc; Thousand Oaks California 91320

3. LabCorp Clinical Trials, Laboratory Corporation of America Holdings; Brentwood Tennessee 37027

4. Medimmune, LLC; Mountain View California 94043

5. Alnylam Pharmaceuticals; Cambridge Massachusetts 02142

6. Charles River Laboratories International, Inc; Reno Nevada 89511

7. BioCytex; Marseille 13010 France

8. Covance Central Laboratory Services; Geneva 1217 Switzerland

9. Eurofins Pharma Bioanalysis Services UK Limited; Park Abingdon OX14 4RY United Kingdom

10. ICON Laboratory Services; Farmingdale New York 11735

11. PRA Healthsciences; Assen TK 9407 The Netherlands

12. Xintela AB; Lund SE-223 81 Sweden

13. Takeda Pharmaceuticals; Cambridge Massachusetts 02139

14. Covance Central Laboratory Services; Indianapolis Indiana 46214

Publisher

Wiley

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cyto.b.21355/fullpdf

Reference47 articles.

1. Precision medicine: an approach to R&D for delivering superior medicines to patients;Dolsten;Clin Transl Med,2012

2. Population pharmacokinetic/pharmacodynamic analysis of CCR5 receptor occupancy by maraviroc in healthy subjects and HIV-positive patients;Rosario;Br J Clin Pharmacol,2008

3. Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework;Cook;Nat Rev Drug Discov,2014

4. 2005 http://purl.access.gpo.gov/GPO/LPS119812

5. MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study;Vergunst;Arthritis Rheum,2009

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