Mathematical modeling of receptor occupancy data: A valuable technology for biotherapeutic drug development-Reference-Cited by-同舟云学术

Mathematical modeling of receptor occupancy data: A valuable technology for biotherapeutic drug development

Published:2015-10-01 Issue:2 Volume:90 Page:230-236
ISSN:1552-4949
Container-title:Cytometry Part B: Clinical Cytometry
language:en
Short-container-title:Cytometry

Author:

Spilker Mary E.¹,Singh Pratap²,Vicini Paolo¹³

Affiliation:

1. Department of Pharmacokinetics, Dynamics and Metabolism-New Biological Entities; Pfizer Worldwide Research and Development; San Diego California

2. Department of Pharmacokinetics, Dynamics and Metabolism-New Biological Entities; Pfizer Worldwide Research and Development; Cambridge Massachusetts

3. Clinical Pharmacology, Drug Metabolism and Pharmacokinetics, MedImmune; Cambridge UK

Publisher

Wiley

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cyto.b.21318/fullpdf

Reference26 articles.

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3. Approximations of the target-mediated drug disposition model and identifiability of model parameters;Gibiansky;J Pharmacokinet Pharmacodyn,2008

4. Theoretical considerations of target-mediated drug disposition models: Simplifications and approximations;Ma;Pharm Res,2012

5. General pharmacokinetic model for drugs exhibiting target-mediated drug disposition;Mager;J Pharmacokinet Pharmacodyn,2001

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