Hepatocyte Deletion of Triglyceride‐Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice-Reference-Cited by-同舟云学术

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Hepatocyte Deletion of Triglyceride‐Synthesis Enzyme Acyl CoA: Diacylglycerol Acyltransferase 2 Reduces Steatosis Without Increasing Inflammation or Fibrosis in Mice

Published:2019-06-26 Issue:6 Volume:70 Page:1972-1985
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Gluchowski Nina L.¹²³,Gabriel Katlyn R.²³⁴,Chitraju Chandramohan²³,Bronson Roderick T.⁵,Mejhert Niklas²³,Boland Sebastian²³,Wang Kun²³,Lai Zon Weng²³,Farese Robert V.²³⁶,Walther Tobias C.²³⁴⁶

Affiliation:

1. Division of Gastroenterology and Nutrition Boston Children's Hospital Boston MA

2. Department of Genetics and Complex Diseases Harvard T.H. Chan School of Public Health Boston MA

3. Department of Cell Biology Harvard Medical School Boston MA

4. Howard Hughes Medical Institute Boston MA

5. Rodent Histopathology Core Harvard Medical School Boston MA

6. Broad Institute of Harvard and Massachusetts Institute of Technology Cambridge MA

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

NASPGHAN Foundation

Publisher

Wiley

Subject

Hepatology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hep.30765

Reference41 articles.

1. Clinical epidemiology and disease burden of nonalcoholic fatty liver disease

2. Natural history of nonalcoholic fatty liver disease: A prospective follow‐up study with serial biopsies

3. An update on the pharmacological treatment of nonalcoholic fatty liver disease: Beyond lifestyle modifications

4. Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management

5. Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

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