Inhibitory and Activating Effects of Some Flavonoid Derivatives on Human Pyruvate Kinase Isoenzyme M2-Reference-Cited by-同舟云学术

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Inhibitory and Activating Effects of Some Flavonoid Derivatives on Human Pyruvate Kinase Isoenzyme M2

Published:2015-12-28 Issue:2 Volume:349 Page:132-136
ISSN:0365-6233
Container-title:Archiv der Pharmazie
language:en
Short-container-title:Arch. Pharm. Chem. Life Sci.

Author:

Adem Sevki¹,Aslan Abdulselam²,Ahmed Ishtiaq³⁴,Krohn Karsten⁴,Guler Caglar¹,Comaklı Veysel⁵,Demirdag Ramazan⁵,Kuzu Muslum⁵

Affiliation:

1. Department of Chemistry, Faculty of Science; Cankiri Karatekin University; Cankiri Turkey

2. Faculty of Engineering; Giresun University; Giresun Turkey

3. Institute for Biological Interfaces (IBG-1); Karlsruhe Institute of Technology (KIT); Eggenstein-Leopoldshafen Germany

4. Department of Organic Chemistry; University of Paderborn; Paderborn Germany

5. Faculty of Pharmacy; Agrı Ibrahim Cecen University; Agri Turkey

Publisher

Wiley

Subject

Drug Discovery,Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ardp.201500357/fullpdf

Reference25 articles.

1. Targeting glucose metabolism for cancer therapy

2. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

3. M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth

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