Low‐frequency variants in mildly symptomatic vaccine breakthrough infections presents a doubled‐edged sword

Author:

Magalis Brittany R.12ORCID,Mavian Carla12ORCID,Tagliamonte Massimiliano12,Rich Shannan N.134,Cash Melanie12,Riva Alberto5,Loeb Julia C.16,Norris Michael16,Amador David M.5,Zhang Yanping5,Shapiro Jerne34,Starostik Petr2,Marini Simone13,Myers Paul4,Ostrov David A.2,Lednicky John A.16,Glenn Morris J.17,Lauzardo Michael147,Salemi Marco12

Affiliation:

1. Emerging Pathogens Institute University of Florida Gainesville Florida USA

2. Department of Pathology University of Florida Gainesville Florida USA

3. Department of Epidemiology, College of Public Health and Health Professions and College of Medicine University of Florida Gainesville Florida USA

4. Florida Department of Health Gainesville Florida USA

5. Interdisciplinary Center for Biotechnology Research University of Florida Gainesville Florida USA

6. Department of Environmental and Global Health University of Florida Gainesville Florida USA

7. Division of Infectious Diseases and Global Medicine, College of Medicine University of Florida Gainesville Florida USA

Funder

National Science Foundation

Publisher

Wiley

Subject

Infectious Diseases,Virology

Reference51 articles.

1. RambautA LomanN PybusO et al. Preliminary genomic characterisation of an emergent SARS‐CoV‐2 lineage in the UK defined by a novel set of spike mutations.Virologicalorg;2020.https://virological.org/t/preliminary-genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-the-uk-defined-by-a-novel-set-of-spike-mutations/563

2. A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

3. CDC.SARS‐CoV‐2 Variant Classifications and Definitions. Accessed on February 9 2022.https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-classifications.html

4. Phylogenetic evidence that B.1.1.7 has been circulating in the United States since early‐ to mid‐November;Larsen B;Virologicalorg,2021

5. Detection of a SARS-CoV-2 variant of concern in South Africa

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