The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells-Reference-Cited by-同舟云学术

The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells

Published:2019-08-29 Issue:20 Volume:6 Page:1901299
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Adv. Sci.

Author:

Wang Qixue¹,Liu Xing²,Zhou Junhu¹,Yang Chao¹,Wang Guangxiu¹,Tan Yanli³,Wu Ye¹,Zhang Sijing¹,Yi Kaikai¹,Kang Chunsheng¹^ORCID

Affiliation:

1. Tianjin Medical University General HospitalTianjin Neurological InstituteKey Laboratory of Post‐neurotrauma Neuro‐repair and Regeneration in Central Nervous SystemMinistry of Education and Tianjin CityDepartment of NeurosurgeryTianjin Medical University General Hospital Tianjin 300052 China

2. Beijing Neurosurgical InstituteCapital Medical University Beijing 100050 China

3. Department of PathologyMedical College of Hebei University Baoding Hebei 071000 China

Funder

National Basic Research Program of China

Tianjin Science and Technology Committee

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201901299

Reference15 articles.

1. RNA-based drugs and vaccines

2. C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

3. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection

4. Cas13-induced cellular dormancy prevents the rise of CRISPR-resistant bacteriophage

5. Nucleic acid detection with CRISPR-Cas13a/C2c2

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