Trichloroethylene exposure results in the phosphorylation of histone H2AX in a human hepatic cell line through cytochrome P450 2E1-mediated oxidative stress
Author:
Affiliation:
1. Industrial Toxicology and Health Effects Research Group; National Institute of Occupational Safety and Health; Japan
2. Graduate Division of Nutritional and Environmental Sciences; University of Shizuoka; Japan
Funder
Ministry of Education, Culture, Sports, Science and Technology
Publisher
Wiley
Subject
Toxicology
Reference37 articles.
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2. GammaH2AX and cancer;Bonner;Nature Reviews Cancer,2008
3. Trichloroethylene exposure and specificc somatic mutations in patients with renal cell carcinoma;Brauch;Journal of the National Cancer Institute,1999
4. VHL mutations in renal cell cancer: Does occupational exposure to trichloroethylene make a difference?;Brauch;Toxicology Letters,2004
5. ATM phosphorylates histone H2AX in response to DNA double-strand breaks;Burma;Journal of Biological Chemistry,2001
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