CRP Albumin Ratio: A novel noninvasive and cost‐effective method for assessing the severity of acute pancreatitis

Author:

Ghaffar Sania1,Shahnoor Syeda2ORCID,Khan Abdul Moiz1ORCID,Asif Aimen1,Fida Maryam1,Oduoye Malik Olatunde3ORCID,Nafula Wechuli Polyne4ORCID

Affiliation:

1. Department of Internal Medicine Ayub Medical College Abbottabad Pakistan

2. Department of Internal Medicine Dow University of Health Sciences Karachi Pakistan

3. Department of Research at Medical Research Circle in Bukavu Democratic Republic of Congo Bukavu Congo

4. Department of clinical medicine Jomo Kenyatta University of Agriculture and Technology Nairobi Kenya

Abstract

AbstractIntroductionAcute pancreatitis is a significant and potentially life‐threatening gastrointestinal disorder that requires prompt and accurate diagnosis for effective treatment. Current diagnostic methods often involve expensive and inaccessible imaging studies, such as CT scans, limiting their utility in emergency settings and underserved areas.AimThis correspondence discusses an innovative and cost‐effective approach to assessing the severity of acute pancreatitis, focusing on the C‐Reactive Protein‐Albumin Ratio (CAR).MethodologyWe searched relevant articles and studies from 2015 till date on PubMed, Web of Science, and Google Scholar using these keywords: “C‐Reactive Protein”, “Albumin Ratio”, “Acute pancreatitis”, “Cost‐effective”, “Non‐invasive”, and “Severity”.ResultThe CAR diagnostic method involves a simple blood test that measures the levels of C‐Reactive Protein (CRP) and albumin, both commonly used markers for assessing inflammation. Elevated CRP and decreased albumin levels are indicative of inflammation, and the CAR has shown a strong positive correlation with the severity of acute pancreatitis. This method offers a non‐invasive, time‐efficient, and cost‐friendly alternative to traditional diagnostic techniques.ConclusionThe potential of CAR as an assessment tool for the severity of acute pancreatitis is highlighted, especially in resource‐limited settings. This innovation holds promise for improving the timely and accurate diagnosis of acute pancreatitis, ultimately enhancing patient outcomes and reducing mortality rates.

Publisher

Wiley

Subject

General Medicine

Reference12 articles.

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4. Accuracy of neutrophil to lymphocyte ratio (NLR) as a predictor of severe acute pancreatitis keeping balthazar CT scan severity index score as gold standard;Rind W;Anna Roma Soc Cell Biol,2022

5. CT evaluation of acute pancreatitis and its prognostic correlation with CT severity index;Raghuwanshi S;J Clin Diagnos Res,2016

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