DNA Damage and Cellular Senescence in Osteoarthritis: An Unexpected Role for Interferon Regulatory Factor 1 in Chondrocyte DNA Repair
Author:
Affiliation:
1. University of North Carolina, Chapel Hill, and North Carolina State University Raleigh
2. University of North Carolina School of Medicine Chapel Hill
Funder
National Institute on Aging
Publisher
Wiley
Reference23 articles.
1. Cellular senescence and senolytics: the path to the clinic
2. Mechanisms and therapeutic implications of cellular senescence in osteoarthritis
3. Senescent cells and osteoarthritis: a painful connection
4. A phase 2, randomized, double-blind, placebo-controlled study of senolytic molecule UBX0101 in the treatment of painful knee osteoarthritis
5. Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis
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