Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor-Reference-Cited by-同舟云学术

Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor

Published:2014-10-13 Issue:2 Volume:112 Page:308-321
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Raven Nicole¹,Rasche Stefan¹,Kuehn Christoph¹,Anderlei Tibor²,Klöckner Wolf³,Schuster Flora⁴,Henquet Maurice⁵,Bosch Dirk⁵⁶,Büchs Jochen⁷,Fischer Rainer¹⁴,Schillberg Stefan¹⁸

Affiliation:

1. Fraunhofer Institute for Molecular Biology and Applied Ecology IME; Forckenbeckstrasse 6; 52074 Aachen Germany

2. Adolf Kühner AG; Dinkelbergstrasse 1; 4127 Birsfelden Switzerland

3. Bayer Technology Services; Kaiser-Wilhelm-Allee; 51368 Leverkusen Germany

4. RWTH Aachen University; Institute for Molecular Biotechnology; Worringerweg 1 52074 Aachen Germany

5. Plant Research International; PRI Bioscience; Droevendaalsesteeg 1 6700AP Wageningen The Netherlands

6. Department of Membrane Biochemistry and Biophysics; Utrecht University; Padualaan 8 3584 CH Utrecht The Netherlands

7. RWTH Aachen University; AVT - Biochemical Engineering; Worringerweg 1 52074 Aachen Germany

8. Justus-Liebig University Giessen; Institute for Phytopathology and Applied Zoology; Phytopathology Department; Heinrich-Buff-Ring 26-32 35392 Giessen Germany

Funder

European Commission

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference84 articles.

1. High efficiency transformation of cultured tobacco;An;Plant Physiol,1985

2. Expanded-bed chromatography in primary protein purification;Anspach;J Chromatogr A,1999

3. Expanded bed adsorption process for protein recovery from whole mammalian cell culture broth;Batt;Bioseparation,1995

4. Direct coupling of expanded bed adsorption with a downstream purification step;Beck;Bioseparation,1999

5. Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma;Bendandi;Ann Oncol,2010

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