A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins
Author:
Affiliation:
1. Department of Biological Sciences Columbia University New York New York USA
2. Merck & Co., Inc. Kenilworth New Jersey USA
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.28074
Reference19 articles.
1. Multigene expression in stable CHO cell pools generated with the piggyBac transposon system
2. Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system
3. NADPH-dependent GMP reductase isoenzyme of human (GMPR2)
4. IRES-mediated Tricistronic vectors for enhancing generation of high monoclonal antibody expressing CHO cell lines
5. Quantitative analysis of purine and pyrimidine metabolism in Chinese hamster ovary cells
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