In vitrometabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s-Reference-Cited by-同舟云学术

In vitrometabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s

Published:2015-01-24 Issue:3 Volume:36 Page:163-173
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Joo Jeongmin¹,Wu Zhexue¹,Lee Boram¹,Shon Jong Cheol¹,Lee Taeho¹,Lee In-Kyu²,Sim Taebo³,Kim Kyung-Hee⁴,Kim Nam Doo⁴,Kim Seong Heon⁴,Liu Kwang-Hyeon¹

Affiliation:

1. College of Pharmacy and Research Institute of Pharmaceutical Sciences; Kyungpook National University; Daegu 702-701 Korea

2. Department of Internal Medicine; Kyungpook National University Hospital, Kyungpook National University School of Medicine; Daegu 700-721 Korea

3. Chemical Kinomics Research Center; Korea Institute of Science and Technology; Seoul 136-791 Korea

4. New Drug Development Center; Daegu-Gyeongbuk Medical Innovation Foundation; Daegu 701-310 Korea

Funder

National Research Foundation of Korea

Ministry of Health & Welfare, Korea

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.1929/fullpdf

Reference28 articles.

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4. Orphan nuclear receptor estrogen-related receptor gamma (ERRgamma) is key regulator of hepatic gluconeogenesis;Kim;J Biol Chem,2012

5. Inverse agonist of nuclear receptor ERRgamma mediates antidiabetic effect through inhibition of hepatic gluconeogenesis;Kim;Diabetes,2013

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