Chemokine (C-C motif) receptor 2-positive monocytes aggravate the early phase of acetaminophen-induced acute liver injury

Author:

Mossanen Jana C.12,Krenkel Oliver1,Ergen Can1,Govaere Olivier3,Liepelt Anke1,Puengel Tobias1,Heymann Felix1,Kalthoff Sandra4,Lefebvre Eric5,Eulberg Dirk6,Luedde Tom1,Marx Gernot2,Strassburg Christian P.4,Roskams Tania3,Trautwein Christian1,Tacke Frank1

Affiliation:

1. Department of Medicine III; University Hospital Aachen; Aachen Germany

2. Department of Intensive and Intermediate Care; University Hospital Aachen; Aachen Germany

3. Department of Imaging & Pathology; University of Leuven; Leuven Belgium

4. Department of Medicine I; University Hospital Bonn; Bonn Germany

5. Tobira Therapeutics, Inc.; South San Francisco CA

6. NOXXON Pharma AG; Berlin Germany

Funder

German Research Foundation (DFG)

Interdisciplinary Center for Clinical Research (IZKF) Aachen

B. Braun Foundation

Publisher

Wiley

Subject

Hepatology

Reference41 articles.

1. Acetaminophen-induced acute liver injury in mice;Mossanen;Lab Anim,2015

2. Understanding paracetamol-induced liver failure;Larsen;Intensive Care Med,2014

3. Immune mechanisms in acetaminophen-induced acute liver failure;Krenkel;Hepatobiliary Surg Nutr.,2014

4. Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury;Bechmann;J Hepatol,2010

5. The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice;Martin-Murphy;Toxicol Lett,2010

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