Alterations in RD INK4/ARF -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck

Author:

Poi Ming J.1,Knobloch Thomas J.23,Sears Marta T.2,Warner Blake M.2,Uhrig Lana K.2,Weghorst Christopher M.23,Li Junan23

Affiliation:

1. Department of Pharmacy; The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute; The Ohio State University; Columbus Ohio

2. Division of Environmental Health Sciences; College of Public Health; The Ohio State University; Columbus Ohio

3. Comprehensive Cancer Center; The Ohio State University; Columbus Ohio

Funder

NIH

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference30 articles.

1. The RB and p53 pathways in cancer;Sherr;Cancer Cell,2002

2. The regulation of INK4/ARF in cancer and aging;Kim;Cell,2006

3. Cyclin D-dependent kinases, INK4 inhibitors and cancer;Ortega;Biochim Biophys Acta,2002

4. Regulatory mechanisms of tumor suppressor P16INK4A and their relevance to cancer;Li;Biochemistry,2011

5. Oncogenic activity of Cdc6 through repression the INK4/ARF locus;Gonzalez;Nature,2006

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