Antitumor activity of RT2 peptide derived from crocodile leukocyte peptide on human colon cancer xenografts in nude mice

Author:

Maraming Pornsuda1ORCID,Klaynongsruang Sompong2,Boonsiri Patcharee3,Maijaroen Surachai2,Daduang Sakda4,Chung Jing-Gung5ORCID,Daduang Jureerut6

Affiliation:

1. Biomedical Sciences Program; Graduate School, Khon Kaen University; Khon Kaen Thailand

2. Protein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Faculty of Science, Department of Biochemistry; Khon Kaen University; Khon Kaen Thailand

3. Faculty of Medicine, Department of Biochemistry; Khon Kaen University; Khon Kaen Thailand

4. Division of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Science; Khon Kaen University; Khon Kaen Thailand

5. Department of Biological Science and Technology, College of Biopharmaceutical and Food Sciences; China Medical University; Taichung Taiwan, ROC

6. Center for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences; Khon Kaen University; Khon Kaen Thailand

Funder

Khon Kaen University research grant

National Research Council of Thailand

The Royal Golden Jubilee (RGJ) Ph.D. Scholarship

Khon Kaen University

Thailand Research Fund

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Reference41 articles.

1. Inflammatory bowel disease, colorectal cancer and type 2 diabetes mellitus: the links;Jurjus;BBA Clin.,2016

2. Regulation of colon cancer recurrence and development of therapeutic strategies;Kanwar;World J Gastroint Pathophysiol.,2012

3. Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis;Zou;Int J Nanomedicine.,2016

4. Medicinal plants: a potential source of compounds for targeting cell division;Zulkipli;Drug Target Insights.,2015

5. Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds;Chen;Mitochondrion,2010

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2. Research Progress on Anti -tumour, Anti-microbial and Anti-viral Activities of Crocodile Blood;2023 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO);2023-07-31

3. Proteomic profiling reveals antitumor effects of RT2 peptide on a human colon carcinoma xenograft mouse model;European Journal of Pharmacology;2022-02

4. Crocodile blood supplementation protects vascular function in diabetic mice;Food Production, Processing and Nutrition;2021-08-03

5. Potential of crocodile blood as a medication and dietary supplement: A systemic review;Clinical and Experimental Pharmacology and Physiology;2021-05-29

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