Robust physiologically based pharmacokinetic model of rifampicin for predicting <scp>drug–drug</scp> interactions via P‐glycoprotein induction and inhibition in the intestine, liver, and kidney-Reference-Cited by-同舟云学术

Robust physiologically based pharmacokinetic model of rifampicin for predicting drug–drug interactions via P‐glycoprotein induction and inhibition in the intestine, liver, and kidney

Published:2022-06-06 Issue:7 Volume:11 Page:919-933
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacom & Syst Pharma

Author:

Asaumi Ryuta¹,Nunoya Ken‐ichi¹,Yamaura Yoshiyuki¹,Taskar Kunal S.²,Sugiyama Yuichi³

Affiliation:

1. Pharmacokinetic Research Laboratories Ono Pharmaceutical Co., Ltd. Ibaraki Japan

2. Drug Metabolism and Pharmacokinetics In Vitro In Vivo Translation GlaxoSmithKline R&D Stevenage UK

3. Laboratory of Quantitative System Pharmacokinetics/Pharmacodynamics, School of Pharmacy Josai International University Tokyo Japan

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12807

Reference47 articles.

1. Pharmacokinetic Interactions with Rifampicin

2. Organic Anion Transporting Polypeptide (OATP)1B1 and OATP1B3 as Important Regulators of the Pharmacokinetics of Substrate Drugs

3. Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies

4. Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity

5. Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P-gp Inhibition

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