The role of tyrosine 71 in modulating the flap conformations of BACE1
Author:
Funder
National Institutes of Health
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.23050/fullpdf
Reference43 articles.
1. Alzheimer disease: mechanistic understanding predicts novel therapies;Selkoe;Ann Intern Med,2004
2. Alzheimer's disease;Blennow;Lancet,2006
3. Beta-secretase inhibition for the treatment of Alzheimer's disease-promise and challenge;Citron;Trends Pharmacol Sci,2004
4. BACE1 is the major beta-secretase for generation of Abeta peptides by neurons;Cai;Nat Neurosci,2001
5. Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation;Luo;Nat Neurosci,2001
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A computational study of buckyballs as potential inhibitors of BACE1 in Alzheimer’s treatment;Chemical Physics Letters;2024-11
2. Edaravone N-benzyl pyridinium derivatives: BACE-1 inhibition, kinetics and in silico binding pose determination;European Journal of Pharmaceutical Sciences;2024-10
3. Structural and molecular insights into tacrine-benzofuran hybrid induced inhibition of amyloid-β peptide aggregation and BACE1 activity;Journal of Biomolecular Structure and Dynamics;2023-04-04
4. Deciphering the Molecular Mechanism of Inhibition of β‐Secretase (BACE1) Activity by a 2‐Amino‐imidazol‐4‐one Derivative;ChemistrySelect;2022-10-19
5. Identification of potential lead compounds against BACE1 through in-silico screening of phytochemicals of Medhya rasayana plants for Alzheimer's disease management;Computers in Biology and Medicine;2022-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3