Analysis of water patterns in protein kinase binding sites

Author:

Barillari Caterina,Duncan Anna L.,Westwood Isaac M.,Blagg Julian,van Montfort Rob L. M.

Funder

The Institute of Cancer Research

Cancer Research UK [CRUK]

EPSRC

NHS funding to the NIHR Biomedical Research Centre

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Reference45 articles.

1. Targeting cancer with small molecule kinase inhibitors;Zhang;Nat Rev Cancer,2009

2. Protein kinase inhibitors: insights into drug design from structure;Noble;Science,2004

3. The conformational plasticity of protein kinases;Huse;Cell,2002

4. Rational design of inhibitors that bind to inactive kinase conformations;Liu;Nat Chem Biol,2006

5. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571);Nagar;Cancer Res,2002

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